Author
Duke UniversityORCID 0000-0002-0408-0728Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Ankita Singh, Kara M. Anasti, Elizabeth S. Van Itallie…·S. Munir Alam
The paper shows that B cell receptor signaling sets limits on the selection of functional mutations in antibodies, with mid-affinity antigens showing optimal neutralization.
Aaron J. May, Muralikrishna Lella, Jared J. Lindenberger…·Priyamvada Acharya
This study investigates the structural and antigenic diversity of Henipavirus and Parahenipavirus glycoproteins using cryo-EM and crystal structures, revealing new epitopes and insights for vaccine development.
Parker J. Jamieson, Xiaoying Shen, Alexandra A. Abu-Shmais…·Ivelin S. Georgiev
The paper isolates glycan-reactive antibodies from HIV-1 vaccine trial participants and finds they neutralize diverse HIV strains and show broad cross-reactivity against other pathogens.
Caitlin Harris, Anyway Brenda Kapingidza, James Emmanuel San…·Mihai L. Azoitei
This paper designs SARS-CoV-2 RBD immunogens that shift immune responses towards conserved epitopes, improving cross-reactivity against variants.
Goda Baddage Rakitha Malewana, Victoria Stalls, Aaron J. May…·Kevin O. Saunders
Non-stabilized SARS-CoV-2 Spike mRNA vaccination in macaques induces B cell lineages targeting conserved epitopes on Omicron variants or cross-neutralizing epitopes on Sarbecoviruses.