Liu Liu

The paper introduces CAMP-14-3-3, a framework that improves 14-3-3 binding prediction by integrating multi-scale biological features and protein language model embeddings, outperforming existing methods.

The paper develops a serum-free 6iL/E4 culture system that enables derivation and maintenance of embryonic stem cells (ESCs) across multiple mammalian species, revealing conserved mechanisms for ESC self-renewal.

This paper shows that MEK2 activation reprograms fibroblasts into endothelial-like cells by enhancing lysosomal activity through the V-ATPase-TFEB axis.

This study identifies a phosphorylation code in 14-3-3 binding motifs that stimulates induced cardiomyocyte formation by disrupting Hdac4 condensates.

This study identifies BRD4 degradation as a method to enhance cardiac reprogramming by inhibiting the JAK/STAT pathway activated by macrophages and oncostatin M.

This paper introduces a method to degrade phospho-14-3-3-binding-motif proteins using a ubiquitin-proteasome system, demonstrating its efficiency and specificity for studying these proteins.

The paper identifies a chemical combination (IMAP) that enhances cardiac reprogramming by suppressing specific C-C chemokine signaling pathways.