Author

Christopher J. Guerriero

University of PittsburghORCID 0000-0002-1046-2300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Jeffrey L. BrodskyiD· 2 shared Anuradha R. Iyer· 1 shared Ashley R. Flory· 1 shared Chaowei ShangiD· 1 shared Chris Melendez-Suchi· 1 shared Clayton A. WileyiD· 1 shared Hannah E. VorndraniD· 1 shared Jiajun LiuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Jeffrey L. BrodskyORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 21, 2025

Aicardi-Goutieres Syndrome Associated ADAR G1007R mutation dominantly induces neuroinflammation in mouse brain

Xinfeng Guo, Jiajun Liu, Chaowei Shang…·Qingde Wang

This paper describes a mouse model with a human ADAR G1007R mutation that causes neuroinflammation and shows that deleting MDA5 can reverse brain inflammation.

DOI 10.1101/2025.04.21.649787

mouseexperimental assay

𝕏 PostBluesky

Cell BiologyMolecular Biology of the CellPeer-reviewedMar 6, 2024

Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum functions

Melissa J. Mann, Chris Melendez-Suchi, Hannah E. Vorndran…·Teresa M. Buck

This study shows that loss of Grp170 causes ER dysfunction, including BiP misregulation and UPR activation, leading to cell death in mouse embryonic fibroblasts.

13 citations

mouseproteomics

𝕏 PostBluesky