Kamil Pabis

The paper reanalyzes lifespan studies and finds that short-lived controls overestimate intervention efficacy, proposing a 900-day rule to assess confidence in longevity interventions.

The paper investigates the cellular response to mitochondrial dysfunction in mtDNA maintenance disorders using imaging mass cytometry, finding complex-specific upregulation and proteostasis activation.

The paper shows that aging and senescence increase transposon expression through transcriptional readthrough and intron retention, not autonomous transposon activity.

The paper investigates the association between DNA motifs and mitochondrial DNA deletions, finding that triplex motifs negatively correlate with species lifespan after adjusting for other factors.