Jérôme Ambroise

This study investigates the gut microbiota of black soldier fly larvae, revealing a plastic midgut microbiota and a stable hindgut microbiota, with implications for their polyphagous behavior.

This study shows that adipocyte beta3-adrenergic receptor activation protects against high-fat diet-induced cardiac damage by promoting beige fat formation and adipose-cardiac communication.

This study shows that platelet GARP activates TGF-β1 to limit inflammation and promote cardiac repair after myocardial infarction.

This study shows that SMIT1 promotes cardiac hypertrophy and fibrosis in mice under pressure overload by enhancing IP3/Ca2+-dependent signaling pathways.

This study identifies skNAC as critical for maintaining cardiomyocyte integrity and preventing heart failure by regulating proteome homeostasis and metabolic adaptation during pathological hypertrophy.

This study identifies a NRF2/beta3-adrenoreceptor axis that enhances antioxidant defenses and metabolic rewiring via the pentose-phosphate pathway, protecting cardiac function under stress.

This paper develops a multi-parametric simulator to link genetic pathogen data with patient metadata, enhancing pandemic preparedness through synthetic data generation and scenario customization.

This study characterizes multidrug-resistant ESBL-producing K. pneumoniae isolates from a DRC hospital, identifying genetic diversity and resistance patterns.

The paper demonstrates how the VariantExperiment class addresses the need for efficient storage, handling, and sharing of SARS-CoV-2 genomic data and metadata as highlighted by WHO.

This study analyzes genomic data from Vibrio cholerae isolates in eastern DRC to identify genetic clusters and their geographic spread across neighboring countries.

The paper introduces MLVAType, a tool that extracts MLVA profiles from WGS data while maintaining compatibility with traditional MLVA methods, and identifies limitations in k-mer size affecting accuracy.