Okwute Michael Ochayi

This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.

This study shows ATF4 coordinates transcriptomic and structural changes in aging muscle, linking it to mitochondrial dysfunction and suggesting the ISR pathway as a therapeutic target.

This study investigates age-related changes in mitochondrial 3D structure in human skeletal muscle and shows that exercise can restore mitochondrial integrity through mitofusin 2.