Silvia Carnaccini

This study examines sialic acid receptor distribution and H5N1 virus binding in sheep, goats, and alpacas, finding species-specific differences in receptor abundance and virus binding.

The paper develops chicken lung organoids to model avian influenza virus-host interactions and finds they contain diverse cell types and express relevant viral infection genes.

This study uses lectin histochemistry to examine sialic acid receptor distribution in mammary glands of livestock and humans, finding SA 2,6-Gal and SA 2,3-Gal receptors that enable IAV binding.

This study shows that influenza A virus lineage and exposure route affect its spatial distribution and genetic diversity within the respiratory tract of guinea pigs.

This paper develops an in vitro aerosol exposure system to study influenza virus infectivity in different cell types and identifies differences in airborne infectivity among virus strains.

This study shows that dispersal within the respiratory tract affects viral genetic diversity and evolutionary potential, with nasal and tracheal regions maintaining diversity while lung regions show genetic distinctness.

This paper develops a modified live influenza virus vaccine (RAM-IGIP) that enhances humoral and mucosal immunity against influenza, showing complete protection in mice.