Leigh M. Sewall

This paper shows that maternal antiviral history before pregnancy enhances offspring immunity through IgG in milk, which is transferred via FcRn and provides protection beyond weaning.

This study maps polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 vaccines using EMPEM, revealing the NTD supersite as an immunodominant epitope vulnerable to variant mutations.

This study compares bnAb precursor responses in infant and juvenile rhesus macaques after germline-targeting HIV Env immunization, finding higher rates in infants.

The paper identifies anti-immune complex antibodies generated through repeated HIV Env immunizations and presents their structures using polyclonal epitope mapping.

This study immunized cows with HIV Env trimers to generate broadly neutralizing antibodies targeting the V2-apex, revealing ultralong CDRH3 antibodies outcompete shorter ones in the response.

This study shows that a multi-dose immunization with germline-targeting SOSIP vaccines induces precursor broadly neutralizing antibodies in infant macaques, similar to adult responses.