Olivia J. Young

This study demonstrates that DNA origami vaccine nanoparticles enhance both humoral and cellular immune responses against infectious diseases like SARS-CoV-2, HIV, and Ebola.

This paper demonstrates that reusing excess staple oligonucleotides with replenishment can reduce DNA origami production costs by up to 80%.

The paper quantifies cargo on DNA origami nanoparticles using gel-based and fluorescence-based methods for therapeutic applications.

This study developed a DNA origami-based cancer vaccine that co-delivers antigen and CpG immune adjuvant with an optimal nanospacing for Th1 immune polarization.