Alexandre Dubrac

This study identifies SOX9 as a regulator of endothelial tip cell specification in brain and retinal vascularization, showing its role in promoting angiogenesis and revealing differences between developmental and injury-induced vascular responses.

This study shows that metabolic reprogramming in the neurovascular niche promotes regenerative angiogenesis in proliferative retinopathy by shifting metabolism from fatty acid oxidation to glycolysis.

This study identifies a novel angiogenic endothelial cluster driven by loss of ALK1 signaling in brain arteriovenous malformations (bAVMs) and shows that KIT inhibition prevents bAVM formation.