Author

Tianyang Yan

Department of Biological Chemistry, David Geffen School of Medicine, UCLA, Los Angeles, California 90095, United StatesORCID 0000-0002-4941-9828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Keriann M. BackusiD· 2 shared Lisa M. BoatneriD· 2 shared Alexandra C. TurmoniD· 1 shared Ann L. Zhou· 1 shared Ashley R. JulioiD· 1 shared Cameron TayloriD· 1 shared Carina SandovaliD· 1 shared Ernest Armenta· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Keriann M. BackusORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedMay 24, 2024

Chemoproteomics identifies proteoform-selective caspase-2 inhibitors

José O. Castellón, Samuel Ofori, Nikolas R. Burton…·Keriann M. Backus

The paper identifies proteoform-selective caspase-2 inhibitors using chemoproteomics, revealing a unique non-catalytic cysteine and validating their selectivity and activity.

22 citations

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivOct 17, 2023

Defining the Cell Surface Cysteinome using Two-step Enrichment Proteomics

Tianyang Yan, Lisa M. Boatner, Liujuan Cui…·Keriann M. Backus

The paper introduces a two-stage enrichment method called Cys-Surf to profile the cell surface cysteinome, identifying 821 ligandable cysteines and redox-sensitive residues with functional implications.

DOI 10.1021/jacsau.3c00707

humanproteomics

𝕏 PostBluesky