Author
University of California, Los AngelesORCID 0000-0003-2887-8846Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Andrew P. Becker, Elijah Biletch, John Paul Kennelly…·Keriann M. Backus
This paper introduces POCA, a photosensitizer-based proximity labeling method that captures both protein and lipid interactomes with high spatiotemporal resolution.
John Paul Kennelly, Xiao Xu, Yajing Gao…·Peter Tontonoz
The paper identifies cholesterol binding to VCAM-1 as a mechanism promoting vascular inflammation by stabilizing VCAM-1 and enhancing immune cell recruitment.
José O. Castellón, Samuel Ofori, Nikolas R. Burton…·Keriann M. Backus
The paper identifies proteoform-selective caspase-2 inhibitors using chemoproteomics, revealing a unique non-catalytic cysteine and validating their selectivity and activity.
Ashley R. Julio, Flowreen Shikwana, Cindy C. Truong…·Keriann M. Backus
The paper identifies a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14, showing it causes protein aggregation, depletion, and stress granule formation in cells.