Author
University of California, Los AngelesORCID 0000-0002-6258-2849Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Andrew P. Becker, Elijah Biletch, John Paul Kennelly…·Keriann M. Backus
This paper introduces POCA, a photosensitizer-based proximity labeling method that captures both protein and lipid interactomes with high spatiotemporal resolution.
José O. Castellón, Constance Yuen, Brandon Han…·Keriann M. Backus
This study identifies caspase-10 inhibitors using an activation-based high-throughput screen, revealing inhibitors that preferentially target the zymogen form of caspase-10.
José O. Castellón, Samuel Ofori, Nikolas R. Burton…·Keriann M. Backus
The paper identifies proteoform-selective caspase-2 inhibitors using chemoproteomics, revealing a unique non-catalytic cysteine and validating their selectivity and activity.
Ashley R. Julio, Flowreen Shikwana, Cindy C. Truong…·Keriann M. Backus
The paper identifies a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14, showing it causes protein aggregation, depletion, and stress granule formation in cells.