Author

Laurent Bultot

UCLouvainORCID 0000-0002-5088-0101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Luc BertrandiD· 2 shared Alice MarinoiD· 1 shared Alice Parisi· 1 shared Amandine ThomasiD· 1 shared Andreas Unger· 1 shared Anita E. M. KneppersiD· 1 shared B. Bearzatto· 1 shared Benoı̂t ViolletiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPhysiology

Luc BertrandORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintOct 23, 2025

skNAC is a Key Driver of Cardiomyocyte Integrity Against Pathological Cardiac Hypertrophy and Heart Failure

Laura Guilbert, Justine Dontaine, Natacha Fourny…·Luc Bertrand

This study identifies skNAC as critical for maintaining cardiomyocyte integrity and preventing heart failure by regulating proteome homeostasis and metabolic adaptation during pathological hypertrophy.

1 citation

mousehuman

𝕏 PostBluesky

PhysiologyFEBS JournalPeer-reviewedMay 13, 2025

Metformin protects the heart against chronic intermittent hypoxia through AMPK-dependent phosphorylation of HIF-1α

Sophie Moulin, Britanny Blachot‐Minassian, Anita E. M. Kneppers…·Elise Belaïdi

This study shows metformin protects the heart from chronic intermittent hypoxia by activating AMPK2, which phosphorylates and inhibits HIF-1α, reducing mitochondrial damage.

9 citations

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologyThe FASEB JournalPeer-reviewedAug 12, 2019

AMPK promotes induction of a tumor suppressor FLCN through activation of TFEB independently of mTOR

Caterina Collodet, Marc Foretz, Mária Deák…·Kei Sakamoto

The paper identifies the AMPK-TFEB-FLCN axis as a regulator of cellular and metabolic homeostasis through gene expression and functional studies in mice and zebrafish.

74 citations

mousezebrafish

𝕏 PostBluesky