Benedito A. Carneiro

This study shows TTFields increase p21 expression and induce cell death in TNBC cells, with enhanced effects when combined with talazoparib.

This study shows that combining ONC201 with ATR inhibitor ceralasertib synergistically kills ovarian cancer cells by inducing apoptosis and reducing anti-apoptotic proteins.

VGC is a VCF file visualization and analysis tool that provides variant data extraction, visualization, and integration with external databases for gene function and variant interpretation.

This study shows that combining ONC201 with enzalutamide or darolutamide synergistically reduces mCRPC cell viability and PSA levels, with in vivo anti-tumor effects.

This study investigates how senescent fibroblasts influence tumor growth and immune response, showing that targeting the p21-driven SASP and combining senolytics with cancer therapies can suppress tumor growth.

This study shows that androgen receptor inhibitors enhance NK cell-mediated killing of prostate cancer cells and sensitivity to NKG2A checkpoint blockade by upregulating HLA-E expression.