Lei Lei

The paper develops a theoretical model to explain how mechanical properties and cell cycle dynamics regulate volume distribution in germline cysts, leading to oocyte differentiation.

The paper describes a method for culturing postnatal mouse ovaries on membrane inserts to study primordial follicle dynamics and demonstrates its impact on follicle count.

This study shows that senescent primary oocytes contribute to ovarian aging in mice, and their removal improves fertility and follicle numbers.

The paper identifies branched germline cyst structures in mice and shows they facilitate oocyte determination through directional cytoplasmic transport and cyst fragmentation.

This study shows that Tex14 mutant mice have altered germline cysts and oocyte differentiation, linking germ cell connectivity to oocyte cytoplasmic enrichment and adult reproductive lifespan.