Toshihiko Fujimori

This study shows that Wnt11 and core PCP components interact reciprocally to establish cell polarity in Xenopus embryos without relying on Wnt gradients.

The paper shows directional alignment of cell types helps maintain planar cell polarity in tissues with multiple cell types.

The paper develops a theoretical model to explain how mechanical properties and cell cycle dynamics regulate volume distribution in germline cysts, leading to oocyte differentiation.

This study identifies MAP7 as a key regulator of microtubule remodeling in Sertoli cells, essential for apical domain formation and timely meiotic progression in mouse testes.

The paper evaluates mechanical features of cell-cell interactions by relating effective pairwise forces to sub-cellular components using vertex model data.

The paper introduces an improved AID system for efficient endogenous protein degradation and develops a photoactivatable inducer for light-controlled protein knockdown.

The paper shows that ZO-1/ZO-2-deficient cells are selectively eliminated by cell competition, mediated by supracellular actomyosin cables and Hippo signaling, to maintain epithelial barrier homeostasis.

The paper identifies a regulatory loop between CENP-C and Aurora B kinase mediated by the Mis12 complex, essential for correcting kinetochore-microtubule attachment errors during mitosis.

The paper demonstrates mechanical coupling between epithelial cells at apical-apical surfaces during implantation, mediated by extracellular matrix and tight junction molecules.

The paper introduces an ImageJ-based tool for 3D registration between microscopic images, enabling alignment and reconstruction of 3D rotated tissues like mouse embryos and organoids.