Raul Bardini Bressan

The paper develops a spatially and temporally resolved model of small intestinal crypt maintenance using integrated approaches, revealing CBC cells as the main driver of tissue replenishment.

This study uses scRNA-seq to show JAK/STAT signaling creates unique regenerative cell states in ulcerative colitis, altering normal tissue replenishment patterns.

This study benchmarks brain organoid gene co-expression patterns against fetal corticogenesis to assess their alignment with in vivo development.

The paper shows that Brn2 and Ascl1 differentially bind mitotic chromosomes, influencing the timing of transcriptional reactivation during the mitosis-to-G1 transition.

The paper identifies EDC mixtures linked to adverse health outcomes and shows they disrupt gene regulatory networks in vitro and in vivo.