Kim Bak Jensen

The paper shows that mechanical sorting, driven by adhesion and contractility differences, maintains basal-luminal compartmentalization and influences lineage outcomes in glandular epithelia.

The paper uses Deep Visual Proteomics to show that human colon organoids switch to an in vivo-like phenotype after xenotransplantation.

This paper creates a human endoderm organoid cell atlas by integrating single-cell transcriptomes from multiple organoid types to compare cell states with primary tissues and disease models.

The paper shows that mesenchymal Asporin mediates fetal-like reprogramming in regenerating intestinal epithelium by modulating Tgfβ signaling through CD44.

The paper develops a spatially and temporally resolved model of small intestinal crypt maintenance using integrated approaches, revealing CBC cells as the main driver of tissue replenishment.

This study uses scRNA-seq to show JAK/STAT signaling creates unique regenerative cell states in ulcerative colitis, altering normal tissue replenishment patterns.

This study identifies how TGF-β1 modulates cell fate in human ES cell-derived foregut endoderm by inhibiting multiple signaling pathways, promoting pancreas fate over liver.

This study identifies LSD1 as a repressor of a neonatal/reparative gene program in adult intestinal epithelium, showing its role in Paneth cell differentiation and regenerative capacity.