Xiang Yu

miRstring decodes mature miRNA boundaries from precursor context across species and designs artificial miRNAs effectively.

This study identifies FGF21-driven lipolysis in cancer-associated adipocytes as a mechanism causing CD8+T cell dysfunction, showing that targeting this process can enhance cancer immunotherapy.

This study identifies Arabidopsis DXO1 as a diverged ortholog involved in 5'-end RNA quality control, ribosome loading, and mRNA surveillance through its serine-rich N-terminal domain.

The paper identifies post-transcriptional mechanisms coordinating transcription and translation rhythms in Arabidopsis under circadian and stress conditions.

This study identifies GRP7 as a key regulator of ABA-mediated translation efficiency in Arabidopsis by modulating pre-rRNA processing and ribosome distribution.

This study identifies translation inhibitors that enable ex vivo expansion of human hematopoietic stem cells while preserving their function and reducing cytokine exposure.

The paper identifies a non-coding genetic variant associated with SLE that regulates miR-146a expression through a cell-type specific enhancer.

This study identifies TGF-β1 signaling's role in chromatin remodeling that drives glycolysis in pathogenic TH17 cells through epigenetic regulation of metabolic regulators.