Luiz Gustavo Teixeira Alves

The paper quantifies gene expression noise in mammalian cells using single-cell proteomics and finds that noise is largely extrinsic and structured across cellular states.

This study shows that MNK1 and MNK2 have distinct roles in social and cognitive behaviors by regulating different aspects of the synaptic proteome and phosphoproteome in knockout mice.

This study rapidly depletes UPF1 in human cells to investigate NMD-regulated transcriptome dynamics, identifying core transcripts and biological processes affected.

This paper uses neural networks to match disease states between human and hamster COVID-19 scRNAseq data, finding similar cellular responses in specific cell types across species.

This study shows that IGF1R deficiency worsens pneumococcal pneumonia in mice, with increased lung damage and bacterial load, suggesting IGF1R has a protective role.

The paper longitudinally analyzes wastewater viromes to track viral diversity and detect pathogens, identifying thousands of novel viral transcripts.