Xiaojie Zhang

This study determines the atomic structure of mycobacteriophage SWU1 using cryo-EM, revealing key architectural features critical for virion assembly and infection.

The paper identifies lipoamide as a small molecule that dissolves stress granules and improves outcomes in ALS models by modulating redox-sensitive proteins.

The paper describes a protocol for subtomogram averaging to generate high-resolution density maps of helical filaments using cryo-electron tomography, applied to mumps virus nucleocapsids and in-cell forms.