Rong Li

This study shows that increased ovarian ECM stiffness with age impairs follicle function by reducing granulosa cell proliferation and oocyte quality through TGF-β signaling.

This study shows that p53 prevents genome instability by halting cell division under hypo-osmotic stress through G1 arrest and downstream gene activation.

The paper identifies PRR14L as a gene affecting mitotic fidelity and sensitivity to MPS1 inhibition through a CRISPR/Cas9 screen and proximity labeling.

The paper identifies the spatiotemporal coordination of WAVE and N-WASP with actin-bundling proteins to generate invasive protrusions during cell-cell fusion.

The paper identifies TDP43 aggregation at ER-exit sites as a cause of impaired ER-to-Golgi transport in ALS.

This study identifies branched actin polymerization as essential for myoblast fusion during skeletal muscle regeneration, showing its role in forming invasive protrusions for fusion.

This study shows that exposing aged oocytes to a young follicular environment improves their maturation, developmental potential, and mitochondrial function.

This study shows that reducing R-loops in Brca1-knockout mice increases ER-expressing tumors but does not affect tumor incidence.

This paper uses cross-linking mass spectrometry to characterize Hsp70 interactions in budding yeast, revealing self-association, multi-point client interactions, and novel PTMs critical for client function.

The paper uses weighted networks with non-linear activation functions to predict gene essentiality in yeast and suggests biological networks function as distributed systems with unreliable components.