Qing Hua Zhang

The paper identifies CBF-beta as a negative regulator of STING through synthetic lethality screens in VHL-null ccRCC cells, showing its role in type I interferon signaling and tumor growth.

This study identifies a non-catalytic function of SETD2 in maintaining nuclear lamina stability and genome integrity through its N-terminus interactions.

This study shows that the ERG11 mutation, not MRR1A, is primarily responsible for fluconazole resistance in Clade III C. auris isolates, while both mutations modestly affect voriconazole resistance but not other azoles.

This study shows that TAC1B mutations in C. auris increase fluconazole and triazole resistance by upregulating CDR1 and MDR1, with CDR1 being the main driver.

This study identifies PPP2R5D/PP2A holoenzyme as an inhibitor of liprin-1 liquid-liquid phase separation through regulation of phosphorylation sites.

This study identifies MavH as a Legionella effector that promotes membrane-dependent actin polymerization by interacting with PI(3)P and host actin capping proteins.