Author

José Antonio Encinar

Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE)ORCID 0000-0002-7219-3863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Alena PrašnickáiD· 1 shared Ao LiiD· 1 shared Camino de Juan Romero· 1 shared Daria EzeriņaiD· 1 shared David C. HayiD· 1 shared Eduardo Hideo GilglioniiD· 1 shared Elizabeth Pérez-ValencianoiD· 1 shared Eric TrépoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Alena PrašnickáORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2026

Targeting the CDK4-Cyclin D Complex: A New Generation of Selective Kinase Inhibitors for Cancer Therapy

María Fuentes-Baile, José Antonio Encinar, Salomé Araujo‐Abad…·Miguel Saceda

This paper identifies a novel CDK4 inhibitor, diophenic, that selectively targets the CDK4-Cyclin D1 interaction, showing improved selectivity and reduced off-target effects compared to ATP-competitive inhibitors in GBM models.

DOI 10.64898/2026.09.18.752547

humanproteomics

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Cancer BiologyNature CommunicationsPeer-reviewedNov 4, 2024

Protein tyrosine phosphatase receptor kappa regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity

Eduardo Hideo Gilglioni, Ao Li, Wadsen St‐Pierre‐Wijckmans…·Esteban N. Gurzov

This study identifies PTPRK's role in promoting hepatocyte metabolic reprogramming in obesity by regulating glycolysis and lipogenesis, with potential therapeutic implications for obesity-related liver diseases.

33 citationstop 5%

humanmouse

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