Cameron J. Nowell

This study investigates the role of DUSP6 in ADHD by generating DUSP6 knockouts in iPSC-derived dopaminergic neurons, finding increased dopamine secretion and transcriptomic changes linked to neurodevelopment and psychiatric disorders.

This paper develops an expansion microscopy workflow to visualize subcellular features of Breviolum minutum, a cnidarian photosymbiont, overcoming challenges posed by autofluorescence and small size.

This study examines the impact of diabetes on the colonic mucus layer and goblet cells in db/db mice, finding a thinner mucus layer and goblet cell hyperplasia.

This study uses an optogenetic platform to activate a GPCR at different intracellular membranes, showing location-dependent transcriptional responses.

This study profiles transcriptomes of dopaminergic neurons from ADHD and neurotypical iPSCs, identifying DEGs overlapping with ADHD GWAS results and suggesting delayed neuronal maturation.

This paper identifies TRPV4-expressing cell types in the colon and shows limited involvement of TRPV4 in colonic motility.

The paper shows that co-expression of G protein-coupled receptors can lead to emergent cellular behavior through a switch in downstream signaling, specifically demonstrating a reversal of dopamine D2 receptor activity.

The paper shows honey bee queens use different oogenesis checkpoints than workers but share the same molecular pathways for terminating oocyte development.