Franziska Faber

This study uses ASOs to selectively inhibit mRNA translation in Prevotellaceae species, enabling functional analysis and targeted depletion in synthetic communities.

This paper identifies two point mutations in a two-component system that confer vancomycin resistance in C. difficile, revealing a synergistic pathway for resistance in epidemic strains.

This study identifies RbpB as a key RNA-binding protein regulating polysaccharide utilization in gut Bacteroides through post-transcriptional control of PULs.

This paper identifies PrdH as the maturation enzyme required for the formation of the pyruvoyl group in the proline reductase Prd of C. difficile, essential for proline utilization and toxin production.

The paper investigates how inflammatory radicals generate tartaric acid isomers, which serve as transient nutrients for gut pathogens in murine models.

The paper identifies a network of small RNAs that regulate sporulation in C. difficile by modulating translation of the master sporulation regulator Spo0A.