Author
London School of Hygiene & Tropical MedicineORCID 0000-0002-8852-1040Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Xi Ye, Lisl Y. Esherick, Nutpakal Ketprasit…·Stanley C. Xie
The paper identifies potent reaction hijacking inhibitors targeting Plasmodium falciparum asparagine tRNA synthetase, showing high selectivity and resistance refractoriness.
Eduardo Alves, Jack W. Houghton, Lindsay B. Stewart…·Michael J. Delves
Emma Ganga, Rosie Bridgwater, Amke Hackmann…·Mathieu Brochet
This study identifies DCX as essential for microtubule branching in Plasmodium falciparum gametocytes, which is required for mosquito transmission, independent of its role in the conoid.
Henrico Langeveld, Keletso Maepa, Marché Maree…·Lyn‐Marié Birkholtz
The paper identifies PfArk1 as a key target for antimalarial drugs by showing that inhibiting it disrupts parasite mitosis and nuclear division.
Stanley C. Xie, Chia-Wei Tai, Craig J. Morton…·Leann M. Tilley
Penny C. Sparkes, Mufuliat Toyin Famodimu, Eduardo Alves…·Michael J. Delves
The paper shows that mitochondrial ATP synthesis is essential for male gametocyte development in Plasmodium falciparum, highlighting mitochondria as targets for transmission-blocking drugs.
Madeline G. Dans, Coralie Boulet, Gabrielle M. Watson…·Paul R. Gilson
The paper identifies aryl amino acetamides that inhibit Plasmodium falciparum ring development by targeting PfSTART1, a lipid transfer protein, and shows these inhibitors block parasite transmission.