Yitao Huang

This paper develops nanodiscs for targeted delivery of an anti-inflammatory drug to macrophages in AAA, showing reduced disease progression in mice.

This study demonstrates that targeted NAD+ delivery via nanocarriers reduces intimal hyperplasia and promotes endothelial regeneration in a rat model of restenosis.

This study identifies a non-canonical role for PLK4 in fibroblast cell-type transition and shows its regulation by BRD4 and PDGFR pathways, suggesting PLK4 inhibition as a potential anti-fibrotic intervention.

This study shows that PERK inhibition reduces restenosis and thrombosis in animal models, suggesting it as a potential therapeutic strategy for drug-eluting stents.