Author

Francesca Ferrante

Justus-Liebig-Universität GießenORCID 0000-0002-9261-1575Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Benedetto Daniele GiaimoiD· 2 shared Marek BartkuhniD· 2 shared Tilman BorggrefeiD· 2 shared Tobias FriedrichiD· 2 shared Duyen Huynh· 1 shared Franz OswaldiD· 1 shared J. Christof M. GebhardtiD· 1 shared Kefan ZhangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Benedetto Daniele GiaimoORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedFeb 1, 2025

Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding

Duyen Huynh, Philipp Hoffmeister, Tobias Friedrich…·J. Christof M. Gebhardt

The paper investigates RBPJ-DNA binding kinetics and cofactor interactions, finding that kinetic stability, not thermodynamic, governs target site specificity and that mutations affect both association and dissociation rates.

14 citations

humanChIP-seq

𝕏 PostBluesky

GenomicsNucleic Acids ResearchPeer-reviewedApr 5, 2024

Comprehensive Genomic Features indicative for Notch Responsiveness

Benedetto Daniele Giaimo, Tobias Friedrich, Francesca Ferrante…·Tilman Borggrefe

The paper identifies genomic features associated with Notch responsiveness by analyzing RBPJ binding dynamics and develops a machine learning approach to predict Notch responsiveness in different cellular contexts.

2 citations

humanChIP-seq

𝕏 PostBluesky