Emily F. Merritt

The paper uses in vivo single-cell gain-of-function screening to identify latent transcriptional programs that reprogram T cells into synthetic states with enhanced therapeutic potential.

This study shows immune pressure targets Toxoplasma gondii bradyzoites, which mitigate tissue damage and promote host-parasite survival.

This study investigates the role of Toxoplasma gondii type II effector GRA15 in vivo, finding it has a limited impact on brain parasite burden and immune cell numbers at 3 weeks post-infection.

The paper shows that chronic Toxoplasma gondii infection reduces the cytotoxic response of T cells to West Nile virus in the brain, increasing susceptibility to WNV.

This study shows that IFN-γ stimulated murine and human neurons can clear Toxoplasma gondii parasites, challenging the dogma that neurons cannot mount anti-parasitic defenses.

The paper uses RNA-seq to compare transcriptional profiles of neurons infected with Toxoplasma gondii, bystander neurons, and controls, finding immune cell transcripts enriched in infected neurons.