Rajan S. Thakur

This study investigates the roles of VPS13A and BLTP2 in movement disorders using Drosophila models, finding distinct neurodegenerative and synaptic effects.

This study uses a Drosophila nephrocyte model to show that OCRL loss causes endolysosomal defects and kidney dysfunction, which can be rescued by human OCRL but not by mutant variants.

The paper shows PDZD8 promotes autophagy at ER-lysosome contact sites to regulate synaptogenesis through lipid transfer and lysosome maturation.

The paper identifies TRMT9B as a negative regulator of synaptogenesis in Drosophila through genetic screening and biochemical analysis.

The paper identifies genetic variants contributing to clinical heterogeneity in Lowe syndrome by analyzing genomic data from affected family members.