Author

Nayana Iyer

Imperial College LondonORCID 0000-0002-9600-4991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Hasan B. MirzaiD· 2 shared Iain A. McNeishiD· 2 shared Pavlina SpiliopoulouiD· 2 shared Sarah SpeariD· 2 shared A. L. FellowsiD· 1 shared Alexandros SiskosiD· 1 shared Ana P. Costa‐PereiraiD· 1 shared Andrew S. CowburniD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Hasan B. MirzaORCID

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3 papers

Recent·Most cited

Cell BiologyAmerican Journal of Respiratory Cell and Molecular BiologyPeer-reviewedNov 18, 2024

ARF6 as a novel activator of HIF-2alpha in pulmonary arterial hypertension

A. L. Fellows, Chien-Nien Chen, Chongyang Xie…·Beata Wójciak‐Stothard

This study identifies ARF6 as a novel activator of HIF-2alpha in pulmonary arterial hypertension and shows that the antibiotic CTC inhibits this pathway.

7 citations

humanmouse

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 18, 2023

cMYC-mediated immune repression is reversed by inhibition of H3K9/H3K27 methylation maintenance

Isabel CA Dye, Sarah Laing, Ian Garner…·Robert Eldon Brown

This study shows that inhibiting H3K27/H3K9 methylation maintenance reverses cMYC-mediated immune repression in cancer, improving survival in mouse models.

DOI 10.1101/2023.10.18.562888

mousehuman

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 18, 2023

Heme oxygenase-1 expressing omental macrophages as a therapeutic target in ovarian high grade serous carcinoma

Sarah Spear, Olivia Le Saux, Hasan Mirza…·Iain A. McNeish

This study identifies HMOX1-expressing omental macrophages as a therapeutic target and biomarker for poor prognosis ovarian high-grade serous carcinoma.

DOI 10.1101/2023.07.18.549474

mousehuman

𝕏 PostBluesky