Rebecca Devine

This paper shows that MtrAB in Streptomyces venezuelae senses osmotic stress via sucrose, activates ectoine production, and triggers sporulation through direct regulation of bldM and whiI.

The paper investigates redox control of antibiotic biosynthesis in Streptomyces formicae, showing that a redox-sensitive repressor senses oxygen to regulate formicamycin production.

The paper reports new aromatic polyketides called formicapyridines, shows how mutating a single gene increases their production, and identifies a non-catalytic role for ABM superfamily proteins in maintaining biosynthetic pathway fidelity.