Author

Zhi Zheng

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-0867-7334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Kaixian LiuiD· 2 shared Meret ArteriD· 2 shared Scott KeeneyiD· 2 shared Corentin Claeys BouuaertiD· 1 shared David OntosoiD· 1 shared Dinshaw J. PateliD· 1 shared Juncheng WangiD· 1 shared Lyuqin Zheng· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Kaixian LiuORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNaturePeer-reviewedFeb 19, 2025

Reconstitution of SPO11-dependent double-strand break formation

Zhi Zheng, Lyuqin Zheng, Meret Arter…·Scott Keeney

This study reconstitutes SPO11-dependent DNA double-strand break formation in vitro, revealing dimerization-dependent cleavage and topoisomerase activity.

40 citationstop 1%

mouseDNA methylation

𝕏 PostBluesky

BiochemistryNature Structural & Molecular BiologyPeer-reviewedSep 20, 2024

Cryo-EM structure of the Spo11 core complex bound to DNA

You Yu, Juncheng Wang, Kaixian Liu…·Scott Keeney

The paper reports cryo-EM structures of Spo11 core complexes bound to DNA, revealing DNA-binding specificity and structural variation in homologs.

19 citations

yeastcryo-EM

𝕏 PostBluesky