Uwe Schlattner

This paper introduces Carba1, a carbazole-based compound that prevents chemotherapy-induced neuropathy without reducing cancer drug efficacy.

The paper describes an AMPK-based FRET sensor, AMPfret, that detects conformational changes in AMPK upon nucleotide binding, enabling analysis of AMPK activation in vitro and in cells.

This paper investigates how mitochondrial bioenergetics are affected in D2.mdx mice and shows that SBT-20 can improve creatine-dependent bioenergetics by reducing oxidative stress.

The paper shows ACSS2 does not generate butyryl- or crotonyl-CoA from SCFAs, challenging previous assumptions about its substrate specificity.

The paper compares methods to quantify acyl-CoA species in rat liver under normal and ischemic conditions, finding ischemia affects short chain acyl-CoA concentrations differently based on duration.

This study shows that NME1/2 regulate liver response to high-fat diet by repressing de novo lipogenesis and activating protective gene expression through histone acetylation.