Ainara Claveras Cabezudo

This study identifies Atg1-mediated phosphorylation of Atg2 as a mechanism to activate lipid transfer during autophagosome biogenesis.

This study identifies the mechanism of ATG2A-mediated lipid transport in autophagy, revealing N-terminal helices as gates that regulate lipid transfer efficiency.

This study uses molecular dynamics simulations to identify active and inactive states of neurotrophin receptor transmembrane domains and suggests distinct signaling mechanisms for different receptors.

This study maps the structural pathway of class III PI 3-kinase activation by showing how N-myristoylation of VPS15 stabilizes the inactive conformation and how GTP binding promotes activation.

This study identifies FLVCR1 and FLVCR2 as choline and ethanolamine transporters, revealing their structural dynamics and substrate selectivity mechanisms.