Mustafa G. Aydogan

The paper identifies a self-reinforcing ROS-aneuploidy feedback loop in preimplantation development, showing that oxidative stress can induce persistent chromosomal alterations.

The paper identifies a mitochondrial redox switch that licenses the onset of morphogenesis in embryos by showing that mitochondrial superoxide production is critical for this transition.

The paper identifies an autonomous Plk4 oscillator at the base of growing centrioles in Drosophila embryos that times and sets centriole biogenesis duration, independent of the cell cycle.