Marieke M. Glazenburg

This study shows that evolution can restore cellular function without conserving microscopic organization, leading to novel molecular phenotypes in budding yeast.

The paper quantifies Cdc42 polarization dynamics in budding yeast using live cell microscopy and mesoscale observables, revealing stage-specific characteristics and differences in genetic backgrounds.

This study shows that compensatory mutations in yeast rewiring gene fitness across cellular processes, not just individual genes, highlighting the role of functional overlap and network interconnectedness.