Author

Enzo Kingma

Delft University of TechnologyORCID 0009-0003-3742-910XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Liedewij LaaniD· 2 shared Floor Dolsma· 1 shared Karel OlavarríaiD· 1 shared Leila Iñigo de la CruziD· 1 shared Marieke M. GlazenburgiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersEvolutionary Biology

Liedewij LaanORCID

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2 papers

Recent·Most cited

Evolutionary BiologyEMBO ReportsPeer-reviewedFeb 16, 2026

Global genetic rewiring during compensatory evolution in the yeast polarity network

Enzo Kingma, Marieke M. Glazenburg, Karel Olavarría, Liedewij Laan

This study shows that compensatory mutations in yeast rewiring gene fitness across cellular processes, not just individual genes, highlighting the role of functional overlap and network interconnectedness.

4 citations

yeastexperimental assay

𝕏 PostBluesky

Evolutionary BiologyPLoS ONEPeer-reviewedFeb 6, 2025

Saturated Transposon Analysis in Yeast as a One-step Method to Quantify the Fitness Effects of Gene Disruptions on a Genome-Wide Scale

Enzo Kingma, Floor Dolsma, Leila Iñigo de la Cruz, Liedewij Laan

The paper introduces a method to quantify gene disruption fitness effects using TIS data in yeast, showing that average read counts per insertion site provide a robust fitness metric.

5 citations

yeastwhole-genome sequencing

𝕏 PostBluesky