Author
Baylor College of MedicineORCID 0000-0003-2878-4129Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Wen Bu, Tobie D. Lee, Meenakshi Anurag…·Yi Li
This study enables efficient somatic genome editing in rats to model ER+ breast cancer, showing that rat tumors recapitulate key features of human ER+ breast cancer not observed in mice.
Fei Yue, Amy Tsu Ku, Payton D. Stevens…·Yi Li
The paper shows that ZNRF3/RNF43 ubiquitinates and degrades EGFR, and their loss increases EGFR signaling, promoting cancer growth.
Linda Zhang, Joanne I. Hsu, Etienne D. Braekeleer…·Margaret A. Goodell
This study identifies SOD1 as a synthetic lethal target in PPM1D-mutant leukemia cells through CRISPR/Cas9 screening, revealing a dysregulated redox landscape and potential therapeutic strategy.
Anna A. Cook, Sriram Jayabal, Jacky Sheng…·Alanna Jean Watt
This study shows that restoring BDNF-TrkB signaling through exercise or a BDNF mimetic improves motor coordination and cerebellar function in a mouse model of SCA6.