Ken‐ichiro Kamei

This paper presents a method to produce high-purity endothelial cells from human pluripotent stem cells without cell sorting, resulting in cells with arterial-like characteristics comparable to HUVECs.

This paper develops SN38-CA@FC NPs, a ROS-sensitive dimeric prodrug nanoparticle that combines chemotherapy and ferroptosis to treat cancer, showing potent antitumor activity in cell lines and mouse models.

This paper introduces a Brain Organoid-on-a-Chip platform that generates signaling gradients to create topographic forebrain organoids, mimicking human brain regions for neurodevelopment and disease studies.

This paper develops a nanomicelle, SANTA FE OXA, that enhances cancer chemotherapy by inducing ferroptosis and reducing systemic toxicity.

This paper develops a dual-targeted nanoparticulate drug delivery system (SJNP) combining SN38 and JQ-1 to enhance triple-negative breast cancer treatment by disrupting DNA repair and mitochondrial function.

This paper develops a hybrid adipocyte-derived exosome platform for targeted chemo-phototherapy of hepatocellular carcinoma, showing enhanced drug delivery and tumor growth inhibition.

This study modifies a corneal epithelium-on-a-chip model to simulate dry eye syndrome by applying an air-liquid interface stimulus and assesses its effects with and without diclofenac.