Raphael J. Morscher

This study investigates how MMUT deficiency affects mitochondrial energy production in different cell types and variants, finding cell-type and variant-dependent effects.

This study identifies histidine depletion as an antileukemic strategy in T-ALL by revealing its role in suppressing cholesterol biosynthesis through ribosome stalling and GCN2 activation.

This paper shows that combining dietary restriction of arginine and proline with polyamine depletion drugs enhances tumor differentiation and survival in a neuroblastoma mouse model by disrupting oncogenic translation.

This study shows that GLUD1 controls muscle stem cell differentiation by regulating mitochondrial glutamate levels and the malate-aspartate shuttle.