Hannes Becher

The paper presents high-quality genome assemblies for five African cattle breeds using PacBio HiFi sequencing, achieving high contiguity and completeness.

The paper quantifies signalling effects of CTNNB1 mutations across cancer types and finds weakly activating mutations correlate with worse prognosis in hepatocellular carcinoma.

The paper introduces randPedPCA, an R package for rapid PCA of large pedigrees using sparse matrices and randomised linear algebra, demonstrating its efficiency on simulated and real datasets.

The paper shows that chromosome ageing, marked by increased chromatid separation and cohesin depletion, occurs in primordial follicles in both mouse and human oocytes.

The paper develops a model to analyze Hill-Robertson interference in non-recombining genomes, showing accurate approximations for mutation frequencies and genetic diversity.

The paper shows that some Shh enhancers can activate transcription of both Shh and Mnx1 genes across a TAD boundary, supporting a cohesin-dependent hub model for enhancer function.

The paper examines how selection efficacy varies between life stages in the haploid-diploid bryophyte Marchantia polymorpha subsp. ruderalis, finding increased sequence diversity and reduced codon usage bias in diploid-biased genes.

This paper shows that RNA and SAF-A form a microgel network in the nucleus near the sol-gel transition, exhibiting viscoelastic properties and reconciling solid-like and fluid-like behaviors.