Olivier Bernus

This study compares mitochondrial function and TCA cycle activity in sheep resistant to atrial fibrillation (AF) versus those that develop stable AF, finding differences in redox state and energy metabolism.

This paper uses ihMT MRI to differentiate subregions of cardiac Purkinje fibers in sheep hearts, showing higher ihMTR in free-running PF compared to insertion points and myocardium, with histology confirming collagen differences.

This paper develops a deep learning-based method to isolate and classify Purkinje fiber cells from adult sheep hearts using imaging data and validation techniques.

The paper introduces Ithildin, an open-source library for simulating excitable media, demonstrating its use in cardiac electrophysiology simulations.

This study shows that increased spontaneous Ca2+ activity in cardiac Purkinje cells after myocardial infarction is due to a shift in SERCA2 isoforms, specifically increased SERCA2b and reduced SERCA2a.