Danijela Matic Vignjevic

This study shows that multicellular systems coordinate force generation and invasive migration through oscillatory mechanochemical feedback in 3D matrices.

This study investigates how fibronectin matrix remodeling by cancer-associated fibroblasts (CAFs) influences their nematic dynamics, revealing aging and freezing of defect motion in the ECM.

This study shows that frictional forces from cancer-associated fibroblasts induce budding in cancer cell monolayers through a purse-string mechanism, driven by a supracellular contractile ring.

This study identifies six distinct intestinal fibroblast subpopulations in mice using scRNA-seq, maps their spatial distribution, and proposes a standardized nomenclature for improved classification and functional understanding.

This study shows cancer cells follow intrinsic self-organized programs that coordinate tumor cell state transitions during growth, revealing mechanical gradients and stereotyped patterns of heterogeneity and plasticity.

This study shows that mechanical signals from the Collagen I-rich matrix drive fate transitions in colorectal cancer cells, enabling metastasis despite lacking Lgr5 expression.

This study shows PIEZO channels are essential for intestinal stem cell maintenance by sensing mechanical cues from their niche.

The paper shows how mechanical forces from epithelial and mesenchymal compartments coordinate cell shape and fate to form tissue architecture during hair follicle development.