Author

Miguel A. Lorenzo Campos

Northwestern UniversityORCID 0000-0003-4650-1225Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Xiaoyu ZhangiD· 2 shared Alana G. CaldwelliD· 1 shared Ananya A. BasuiD· 1 shared Assa MagassaiD· 1 shared Chen MozesiD· 1 shared Chen ZhouiD· 1 shared Chenlu ZhangiD· 1 shared Felicia KoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Xiaoyu ZhangORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintNov 30, 2025

Covalent Reprogramming of Kinase Binders to Modulate Protein Homeostasis

Chen Mozes, Xiao‐Kang Jin, Miguel A. Lorenzo Campos…·Xiaoyu Zhang

The paper shows that adding electrophilic groups to kinase ligands can stabilize or degrade proteins, demonstrating a new way to modulate protein homeostasis through covalent interactions.

DOI 10.1101/2025.11.30.691461

humanproteomics

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BiochemistryNature Chemical BiologyPeer-reviewedJul 4, 2024

A CRISPR activation screen identifies FBXO22 as an E3 ligase supporting targeted protein degradation

Ananya A. Basu, Chenlu Zhang, Isabella A. Riha…·Xiaoyu Zhang

This study identifies FBXO22 as an E3 ligase that supports ligand-induced protein degradation through PROTACs, expanding the toolkit for targeted protein degradation.

53 citationstop 2%

humangenetic perturbation / CRISPR

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