Author

Anna Gesine Huhn

University of OxfordORCID 0000-0003-4798-4951Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Ana RodriguesiD· 2 shared Angela M. MinassianiD· 2 shared Cassandra A. RigbyiD· 2 shared Charlotte Mary DeaneiD· 2 shared Doris QuinkertiD· 2 shared Jordan R. BarrettiD· 2 shared Kirsty McHughiD· 2 shared Mikhail A. KutuzoviD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Ana RodriguesORCID

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4 papers

Recent·Most cited

ImmunologyImmunityPeer-reviewedJun 12, 2026

Structural basis for synergistic antibody protection against the essential malaria invasion complex protein RIPR

Barnabas G. Williams, Jordan R. Barrett, Josefin Bartholdson Scott…·Simon J. Draper

The paper identifies synergistic antibody interactions against the malaria protein RIPR, showing how combinations of antibodies targeting specific domains inhibit parasite invasion.

1 citationtop 4%

plant (other)experimental assay

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ImmunologybioRxivPreprintDec 26, 2025

Synergistic non-neutralizing plasma antibodies to PfRH5 drive potent malaria parasite growth inhibition

Jeffrey Marchioni, Kirsty McHugh, Jordan R. Barrett…·Jason J. Lavinder

The paper identifies synergistic non-neutralizing antibodies against PfRH5 that enhance malaria parasite growth inhibition when combined with neutralizing antibodies.

DOI 10.64898/2025.12.24.696081

humanproteomics

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ImmunologybioRxivPreprintJan 12, 2025

The 3D affinities of the OT-I TCR to foreign and self-antigens predict their 2D affinities and reveal imperfect antigen discrimination

Anna Gesine Huhn, Mikhail A. Kutuzov, Keir Maclean…·Omer Dushek

This paper measures 3D affinities of the OT-I TCR to 19 pMHC complexes and finds they strongly correlate with 2D membrane affinities, revealing imperfect antigen discrimination.

2 citations

mouseproteomics

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ImmunologyNature CommunicationsPeer-reviewedJan 2, 2025

Analysis of emergent bivalent antibody binding identifies the molecular reach as a critical determinant of SARS-CoV-2 neutralisation potency

Anna Gesine Huhn, Daniel Allen Nissley, Daniel B. Wilson…·Omer Dushek

This paper develops a bivalent binding model to analyze how molecular reach affects SARS-CoV-2 neutralization potency across antibodies.

18 citationstop 1%

virusproteomics

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