Author

Xuan Lü

Cornell UniversityORCID 0000-0003-4886-0918Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hening LiniD· 2 shared Dan HouiD· 1 shared Don-Gerard CondeiD· 1 shared George E. MaioiD· 1 shared Jiaqi ZhaoiD· 1 shared Jiaqi ZhaoiD· 1 shared Kay F. MacleodiD· 1 shared Leah M. Ziolkowski· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Hening LinORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 2, 2026

DHHC7 palmitoylates KRAS4A and promotes mutant KRAS-driven pancreatic cancers

Wenzhe Chen, George E. Maio, Xiao Chen…·Hening Lin

This study identifies DHHC7 as a palmitoyl transferase that modifies KRAS4A, enhancing its membrane localization and activation, and shows that targeting DHHC7 inhibits pancreatic tumor growth.

DOI 10.64898/2026.03.31.715686

humanmouse

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ImmunologyCell ReportsPeer-reviewedApr 1, 2024

NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation

Tao Yu, Dan Hou, Jiaqi Zhao…·Hening Lin

This study identifies ZDHHC7-mediated palmitoylation of NLRP3 at Cys126 as critical for inflammasome activation, with implications for therapeutic targeting of inflammatory diseases.

123 citationstop 1%

mousehuman

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