Ivan Chavez

This study identifies immune-stromal-epithelial communication in CeD duodenum using scRNA-seq, revealing fibroblast-mediated epithelial reprogramming through IL-1β and IFN-γ signals.

This study shows that ECM topography promotes adrenergic to mesenchymal transition in neuroblastoma by enhancing cell-ECM interactions and activating the Rho-associated kinase pathway.

This study identifies differences in cell-ECM interaction between rhabdomyosarcoma subtypes, showing FNRMS has heightened interaction regulated by TGFβ signaling, while PAX3-FOXO1 in FPRMS suppresses this interaction.

This study identifies a spatial mechanism of sensory adaptation in Pseudomonas aeruginosa, revealing how enzyme localization modulates mechanosensing and virulence.